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Hepatitis B Antigen & Antibody medical test

Learn about Hepatitis B Antigen & Antibody medical tests, including what the tests are used for, why a doctor may order a test, how a test will feel, and what the results may mean.


What is Hepatitis B Antigen & Antibody test?

Hepatitis B is an infection of the liver caused by the hepatitis B virus (HBV). Hepatitis B blood tests detect viral proteins (antigens), the antibodies that are produced in response to an infection, or detect or evaluate the genetic material (DNA) of the virus. The pattern of test results can identify a person who has a current active infection, was exposed to HBV in the past, or has immunity as a result of vaccination.

What the Hepatitis B Antigen & Antibody test is used for?

To determine whether acute signs and symptoms, such as jaundice, fever and fatigue, are due to hepatitis B infection; two tests, hepatitis B surface Ag and hepatitis B core antibody IgM, may be performed as part of an acute viral hepatitis panel along with tests for hepatitis A (HAV) and hepatitis C (HCV) to determine which virus may be causing the infection.

How is the procedure performed?

A blood sample drawn from a vein in your arm. You may want to wear a shirt with sleeves that can easily be rolled up to make it easier to collect the blood sample. This usually takes less than five minutes.

What will be the results interprets?

The tests for hepatitis B may be ordered individually but are often ordered in some combination, depending on the reason for testing. Results of the tests are typically evaluated together. Sometimes the meaning of one result depends on the result of another test. However, not all tests are performed for all people.

Interpretation HBsAg HBsAb (anti-HBs) HBcAb (Anti-HBc)
Not Immune - Get Vaccinated

Has not been infected, but still at risk for possible hepatitis B infection. Get the vaccine.
- - -
Immune – Protected

Surface antibodies present due to natural infection. Has recovered from a prior hepatitis B infection. Cannot infect others.
- + +
Immune – Protected

Has been vaccinated. Does not have the virus. No vaccine is needed.
- + -
Infected - Need More Testing

Positive surface antigen (HBsAg), which means hepatitis B virus is present. Can spread the virus to others. Find a doctor who knows about hepatitis B for more tests and care.
+ - +
Could be Infected - Need More Testing

Different interpretations are possible. Person might be infected, susceptible, or have a resolved infection.
- - +